Found 19 matching trials
Open Label Trial Assessing Safety and Efficacy of Burosumab (KRN23), in a Patient With ENS and Hypophosphatemic Rickets PHASE3 A 52 week, open label trial to assess the safety and efficacy of KRN23, an ...
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The Focus Center, PC
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Open Label Study of KRN23 on Osteomalacia in Adults With X-linked Hypophosphatemia (XLH) PHASE3 The primary objective of this study is to establish the effect of KRN23 tre...
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UCSF Medical Center at Mission
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Burosumab in Children and Adolescents With X-linked Hypophosphatemia PHASE4 In this prospective longitudinal cohort study we studied the efficacy and s...
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A Repeated Study of KRN23 in Adults With X-Linked Hypophosphatemia PHASE1 The primary purpose of this study is to assess the safety and efficacy of r...
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University of California, San Francisco Medical Center
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An Extension Study of KRN23 in Adults With X-Linked Hypophosphatemia PHASE1 The primary purpose of this study is to assess the safety and efficacy of r...
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University of California San Francisco
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Study to Assess the Safety, Tolerability, Pharmacokinetics and Efficacy of Burosumab in Patients Less Than 1 Year of Age PHASE1 A Phase 1/2, Open-label, Multicenter, Non-randomized Study to Assess the Sa...
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Kepler Universitaetsklinikum GmbH
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Study of KRN23 (Burosumab), a Recombinant Fully Human Monoclonal Antibody Against Fibroblast Growth Factor 23 (FGF23), in Pediatric Subjects With X-linked Hypophosphatemia (XLH) PHASE2 The objectives of the study are to:
* Identify a dose and dosing regimen o...
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University of California San Francisco
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Examining the Effect of Burosumab on Muscle Function PHASE4 Patients with X-linked hypophosphatemia (XLH) often report symptoms of fati...
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Yale University School of Medicine
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Long-Term Extension Study of KRN23 in Adult Subjects With X-Linked Hypophosphatemia (XLH) PHASE2 The primary objectives of this study are to:
* Assess the long-term safety...
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University California San Francisco Hospital
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Study of the Safety, Pharmacodynamics (PD) and Efficacy of KRN23 in Children From 1 to 4 Years Old With X-linked Hypophosphatemia (XLH) PHASE2 The primary objectives of the study are to:
* Establish the safety profile...
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Yale University School of Medicine
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